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Consider Alternatives If Who Should Avoid Do not use if Pregnant, breastfeeding, or planning to become pregnant You have a personal or family history of medullary thyroid carcinoma (MTC) You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) You have severe gastroparesis or serious GI motility disorders You have an active eating disorder (anorexia, bulimia) You have had a severe allergic reaction to amylin analogs Use with caution if !You have a history of pancreatitis !You have gallbladder disease or history of gallstones !You have diabetic retinopathy !You are taking insulin or sulfonylureas (increased hypoglycemia risk) !You have significant kidney impairment !You have difficulty maintaining adequate nutrition Administration How do I use it

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Whole-joint treatment is often what actually improves pain and function